Tohoku University

Future Global Leadership Program

Degree Courses Taught in English

22nd Tue 01:46:48 UTC    22nd Tue 10:46:48 Asia/Tokyo

Dr. Martin Robert

Associate Professor
Institute for Excellence in Higher Education (IEHE)
Website: Click Here

Martin Robert is Associate Professor at Tohoku University in Sendai, Japan. He teaches biological sciences at the FGL International Undergraduate Program including fundamental courses in cell biology and biochemistry and another course that merges principles of physiology and systems biology. In addition, Martin is actively pursuing research on the metabolic function of E. coli. His interests are centered on functional enzyme genomics using metabolomics, proteomics, and bioinformatics tools, the metabolic response of E. coli during adaptive evolution, and the dynamics and systems biology of this bacterium.

Martin obtained his B.Sc. (1990) and PhD. (1996) in biochemistry from McGill University in his native Montreal, Canada. This was followed by postdoctoral training (1996-2001) in a private pharmaceutical research institute, part of the Chugai-Roche group near Tsukuba, Japan where he worked on cellular aging and cytokine receptors. He also worked as project manager at Euroscreen, a biotech company in Brussels, Belgium (2001-2002). Before joining the faculty at Tohoku University in 2013, Martin was Assistant Professor at the Institute for Advanced Biosciences, a pioneering institute part of Keio University in Japan, the oldest private university in the country. Martin is also concurrently guest lecturer at Yamagata University and affiliate member at the Institute for Advanced Biosciences, Keio University.


  • Life and Nature: Study of Nature, Life and Technology (Fall semester)
  • Biology A - Essential Cell Biology (Fall semester)
  • Biology B - Essential Biochemistry (Spring semester)
  • Biology C - Elements of Physiology and Systems biology: Integrative and systems principles in biology (Spring semester)
  • Introductory Seminar - Intensive Short Course in Marine Biology (intensive course in August-September)

Selected publications

Cheng, K.-K. et al. Global metabolic network reorganization by adaptive mutations allows fast growth of Escherichia coli on glycerol. Nat. Commun. 5:3233 doi: 10.1038/ncomms4233 (2014).

Robert M., Murray, D., Honma M., Nakahigashi K., Soga T., and Tomita M. (2012) Extracellular metabolite dynamics and temporal organization of metabolic function in E. coli. Proceedings of 2012 IEEE/ICME International Conference on Complex Medical Engineering, 197-202.

Saito, N., Robert, M., Kochi, H., Matsuo, G., Kakazu, Y., Soga, T., and Tomita, M. (2009) Metabolite profiling reveals YihU as a novel hydroxybutyrate dehydrogenase for alternative succinic semialdehyde metabolism in Escherichia coli. J. Biol. Chem. 284, 24, 16442-16451

Ishii, N., Nakahigashi, K., Baba, T., Robert, M., Soga, T., Kanai, A., Hirasawa, T., et al. (2007). Multiple High-Throughput Analyses Monitor the Response of E. coli to Perturbations. Science 316, 593-597.

Robert, M., Soga, T., and Tomita, M. (2007) E. coli metabolomics: capturing the complexity of a "simple" model. In: Metabolomics, A Powerful Tool in Systems Biology. Topics in Current Genetics. Eds. Nielsen J. Jewett M. 18, pp 189-234, Springer Berlin/Heidelberg

Baran R., Kochi H., Saito N., Soga T., Nishioka T., Robert M., and Tomita M. (2006) MathDAMP: a package for differential analysis of metabolite profiles. BMC Bioinformatics 7, 53

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